Samstag, 7. März 2026

The Daily

A curated briefing

Wien heute: Trocken und sonnig (ca. 11 Sonnenstunden), maximal 15°C / minimal 5°C. Südostwind um 10 km/h, UV niedrig.

AI & Tech

xAI loses bid to block California’s AI training-data disclosure law

California’s AB 2013 is a simple idea with sharp edges: if you sell an AI model in the state, you should publicly describe the dataset sources you trained on, when you collected them, whether collection is ongoing, and whether the training corpus includes copyrighted material or personal data. Ars Technica reports that xAI sought a preliminary injunction, arguing that dataset sources, sizes and cleaning methods are trade secrets — but the judge denied the request, saying xAI didn’t show concrete, irreparable harm (too many abstractions, too few specifics). The practical consequence isn’t the courtroom drama — it’s the new baseline: “training data transparency” is becoming a compliance surface, not a voluntary blog post.
Source: Ars Technica

CISA adds exploited iOS vulnerabilities — and Google hints at a “second-hand zero-day” market

A sobering nugget in this Ars piece: Google researchers analyzed an iOS exploit kit (“Coruna”) that appears to have been used by multiple distinct threat actors over time — a signal that high-end exploit chains can circulate and get re-used. CISA is adding three Apple CVEs to its Known Exploited Vulnerabilities catalog, which is basically the US government’s “patch this yesterday” list. If you run iOS devices in any managed environment, this is the moment to check fleet versions and push updates — not because the CVE numbers are scary, but because the real-world exploitation is documented.
Source: Ars Technica

Biotech & Pharma

Servier to acquire Day One Biopharmaceuticals for ~$2.5B

Servier and Day One announced a definitive agreement for Servier to acquire Day One for $21.50 per share in cash (total equity value ~$2.5B), with closing expected in Q2 2026. The strategic headline is rare oncology — specifically strengthening Servier’s position in pediatric low‑grade glioma while also adding adult and pediatric pipeline programs ranging from early stage to Phase 3. I like this deal because it reads as “portfolio logic” rather than vibes: Servier already has rare-cancer operating muscle, and Day One brings focused biology plus a patient community that’s often underserved by big-pharma incentive structures.
Source: Servier (press release)

FDA approves teclistamab + daratumumab (subcutaneous) for R/R multiple myeloma after ≥1 prior line

The FDA approved teclistamab (Tecvayli) in combination with daratumumab hyaluronidase-fihj for adults with relapsed/refractory multiple myeloma who have received at least one prior line of therapy (including a proteasome inhibitor and an IMiD). The approval is based on MajesTEC‑3 (N=587): per the ONS summary, median PFS was not reached in the teclistamab+dara arm vs 18.1 months in control (HR 0.17). There’s still a boxed warning for CRS/ICANS and a REMS program, but the direction is clear: bispecifics are marching earlier.
Source: Oncology Nursing Society (citing FDA; MajesTEC‑3)

Science / Immuno-Oncology

Teclistamab plus daratumumab (MajesTEC‑3) — the “earlier line” bispecific era in one Phase 3

The NEJM paper behind this week’s FDA move is worth reading as a template for where myeloma is going. MajesTEC‑3 randomized 587 patients (1–3 prior lines) to teclistamab+daratumumab vs daratumumab+dexamethasone with investigator’s choice of pomalidomide or bortezomib. The study’s core message is not subtle: progression-free survival strongly favors the bispecific combo (the FDA summary cited HR 0.17). The more interesting question now is sequencing: if you pull a BCMA-directed T‑cell engager into second line, what do you do with BCMA CAR‑T later — and which antigens become the new “late-line” real estate?
Source: N Engl J Med (PubMed 41363801)

Expert consensus on CMV management after CAR‑T and bispecific antibodies

As T‑cell redirecting therapies scale, infection prevention becomes a first-class design constraint, not an afterthought. This China-adapted consensus focuses on cytomegalovirus (CMV) risk in CAR‑T and bispecific antibody recipients in a high-seroprevalence setting. Key practical points include early risk stratification, routine qPCR monitoring in the first 30 days, and the push to anchor thresholds to WHO-traceable IU/mL so labs can actually compare results across assays. It’s not flashy science — it’s the sort of operational standardization that quietly reduces non-relapse mortality.
Source: J Evid Based Med (PubMed 41531379)

Wien – Kultur & Essen

Falter-Lokalführer: Wo man in Wien den besten Tofu bekommt

Das ist genau mein Lieblingsformat: konkret, subjektiv, und trotzdem nützlich. Der Falter listet Tofu nicht als „Ersatz“, sondern als eigene Textur-Welt — von der Wiener Tofu-Manufaktur am Karmelitermarkt (frisch produziert und gleich verkocht) über Mapo‑Tofu bei Shu bis zu „Tofu in allen Aggregatzuständen“ im Chili & Pepper Hotpot (Tofuhaut, Frozen Tofu, frittiert). Wenn du am Wochenende kochst: einmal mitnehmen, einmal im Lokal probieren — so lernt man schneller, was Tofu wirklich kann.
Source: FALTER

Kulinarische Highlights zum Wochenende: Weltfrauentag-Events & Saisonstart am Biohof N°5

Rund um den 8. März passiert in Wien gastronomisch gerade viel — nicht nur „Special Menüs“, sondern auch programmatisch (Female Empowerment, Talks, Takeovers). Der Falter bündelt ein paar gute Ankerpunkte: von Weltfrauentag-Events bis zum Saisonstart am Biohof N°5 (Auftakt mit Blunzenfest, draußen im Hochfeld). Das ist Wien in Bestform: du kannst „nur kurz“ auf ein Glas vorbeischauen — und bleibst dann doch länger.
Source: FALTER

Travel

Bari’s Bif&st (March 21–28): a festival excuse to do Apulia before spring crowds

If you want an Italy trip that’s not the usual Rome–Florence–Venice loop, Bari in late March is a clean move. Packing for Puglia summarizes the Bif&st (Bari International Film Festival), running March 21–28 across venues like Teatro Petruzzelli and Kursaal Santalucia. The useful detail: it’s not just screenings — there are masterclasses, seminars and retrospectives, which makes the city feel “programmed” even if you’re not a festival obsessive. Bonus: Apulia is an easy base for day trips (Polignano a Mare, Alberobello) without the summer pricing.
Source: Packing for Puglia

Festival enogastronomici 6–8 marzo: tartufo, radicchio, miele — l’Italia “di provincia” in tre giorni

Un elenco ben fatto per chi viaggia seguendo la tavola (o per chi vuole una scusa per evitare le grandi città). CiboToday seleziona eventi diffusi nel weekend 6–8 marzo: da Cucina a Pordenone (degustazioni, show cooking, masterclass) fino a giornate dedicate al Tartufo Nero Pregiato in Piemonte, e a eventi sul Radicchio Rosso Tardivo nel Trevigiano con mostra mercato, dimostrazioni e — cosa che adoro — laboratori per bambini. È un promemoria: l’Italia migliore spesso non è un “must‑see”, è un calendario locale.
Source: CiboToday.it

NBA News

Starting 5 (March 6): LeBron passes Kareem in FGs, and Tatum’s return watch

NBA.com’s “Starting 5” is basically the league’s own morning briefing, and today’s edition is a neat snapshot of how weirdly stacked this season is. The headline: LeBron James passing Kareem Abdul‑Jabbar for the most field goals made (a record that still feels slightly unreal). Tonight’s spotlight game: Celtics–Mavs on ESPN with Jayson Tatum listed as questionable — his first real “return window” since the Achilles tear. Add the Western Conference shuffle and the MVP ladder notes, and you get a full night that’s less about one marquee matchup and more about standings gravity.
Source: NBA.com

Wien für Kinder

Zaubertag im WITAF: Workshop für Kinder (14:00–17:00)

Ein schöner, sehr konkreter Samstags-Plan: Laut Gebärdenwelt (WITAF-Kalender) gibt’s heute im WITAF einen Zauber‑Workshop für Kinder von 14:00 bis 17:00, mit Anmeldung (Anmeldeschluss war der 5. März). Für Nichtmitglieder gibt es eine Teilnahmegebühr (im Artikel genannt: €3 bis €10). Nebenbei ist es ein guter Hinweis auf ein oft übersehenes Angebot: Veranstaltungen mit ÖGS/Dolmetschung, die viele Familien überhaupt erst zugänglich machen.
Source: WITAF (via Gebärdenwelt.tv)

Wiener Frauenwoche (bis 8.3.): 200+ kostenlose Angebote — inkl. Workshops für Mädchen ab 10

Für Familien mit älteren Kids/Teens: MeinBezirk bündelt das Programm der Wiener Frauenwoche, die sich bis 8. März über alle Bezirke verteilt. Praktisch rausgepickt: das flash Mädchen*café der Wiener Jugendzentren bietet für Mädchen ab 10 einen Workshop zu „Mädchen*rechte – Realitätscheck“. Und heute (7. März) wird das Rathaus als „Offenes Rathaus“ bespielt: Konzerte, Workshops, Filmvorführung, Führungen. Nicht jede Familie hat dafür Zeit — aber als „Stadt ist Bühne“-Samstag ist es eine starke Option.
Source: MeinBezirk Wien